1. Biochem-720 Morning-A and Evening-A (Winter 2023-2024)

 ATopic of presentation (research articles only)

  1. You will present research article and the article should be taken from a journal with more than 6 impact factor or the chosen article may be from the following journals: Cell, Nature, Science, Nature Biotechnology, Molecular Cell, Current Biology, Autophagy, Cell Signaling, The New England Journal of Medicine, NATURE MEDICINE, LANCET ONCOLOGY, NATURE GENETICS, Molecular Plant, Trends in Cancer
  2. You may use key words, to choose your article for presentations: Metabolism, breast cancer, diabetes, signallig pathways, genetic engineering, therapeutic antibodies, enzyme production, genetic engineering in plants, gene therapy, stem cell therapy, immunotherapy, recombinant enzyme, drug discovery, drug screening, moue models, preclinical trials, clinical trials, clinical biochemistry, fermentation biochemistry etc.
  3. Your title of the article can be in the form:
                  Hexokinase-II Positively Regulates Glucose Starvation-Induced Autophagy through TORC1 Inhibition
  4. The articles should not be older than 2018. 
  5. Please don’t select a survey-based article to present.
  6. The article should not be review article but only research article.


B. How to inform me about the article you choose

  • You will go to google forms and will write your name and select you section. Later you will edit your response and will write title of the article you will chose to present. I will make class formation from the filled form.


C. Material to submit before and after the presentation

  1. All students will submit me the page containing the title and two questions for every presentation.
  2. Presenter will submit summary of the article (2 sets)
  3. containing these headings (as shown in D). 


D. General Question to be asked during presentation?

1) Pathway or importance of protein/technology/discovery/drug

2) Rationale/Novelty

3) Conclusion of the full article

4) Conclusion of every figure

5) New findings presented in the article

6) Applications of the findings

7) Future prospective

8) Applications of the work done

9) Principle of every technique used in the research article


E. General instructions for presenter and listeners (The same will be written assignment)

  1. The presentation must be around 15 min long with 5 minutes for question and answer session.
  2. You must make ppt files from the choosen research article (plus material from internet if you want).
  3. You must not miss any figure from the research article.
  4. There must be ~15-20 slides in ppt file.
  5. One slide usually takes 1 to 2 min.
  6. CR/GR must collect and submit all ppt files directly to me by USB.
  7. During listening, every student must write two questions to be asked.
  8. If you feel any problem or problem managing work among members, you can consult me.

F. Marks distribution

  1. Assignment material and PPT, Presentation skills, Question answer (5×2 = 10 marks)
  2. Attendance (5 marks)
  3. Attitude during questions and answers (5 marks)
  4. The students who don’t present at their designated time, their presentation marks will be skipped or they will get low score.

G. What I will teach you? 

  1. I have taught you how to read a research article.
  2. I have taught you the anatomy of research articles.

H. Template for ppt

Download the template ppt file to make your presentation. The link is here (copy this link and paste in a new tab).

Strictly follow the ppt format and it is better if you write and paste your material in the same ppt file. 

I. Presentation set up

  1. we may take extra classes to complete presentations.
  2. If by chance all students could not deliver presentations ….
  3. Then remaining students will record their presentation [slide + voice merged]  (less than 25 min long)… And will send me 10 days before the final exam. We can take practical class or any extra class during the week, therefor come on Monday with prepared presentation.
  4. So no chance of escape..therefore, start preparing your ppts.

If any of you feel any problem in 720 or 703.. first discuss it with your 2 or 3 fellows one by one.. if they don’t help you then ask me.. then I will guide you….


The students who don’t present at their designated time, their presentation marks will be skipped or they will get a low score…

I. How to find the impact factor of a journal?

Write the name of the journal and the word “impact factor” in google.com… you can easily see the impact factor. Or download below given excel list impact factor and check.

 J. How to make a general understanding of the research article?

  1. After reading the abstract and intro…
  2. Understand every figure by reading the caption and then by reading text (in results) about the same figures.
  3. Then read the full article.
  4. Better memorize the discussion…
  5. Reading the article may take 5 days…

Moreover, provide me printed one or two page summary of your article containing  above headings.

L. During Presentations, for EVERY FIGURE and graph, we may ask:

1. The Principle of the experiment.
2. The Reason for doing the experiment.
3. The Physiological importance of the figure.
4. The Conclusions of the figures.
5. Prepare well, objectively and subjectively.

How to search and download an article:

First of all go to google.com and search journal of your interest. Then go to current issue or any issue not older than 2018. Select article and click download. If journal is paid then do as follows:

http://gen.lib.rus.ec/ open page-click other- click scientific article- then search. It contains all articles that are not even available in Yonsei library site.

https://sci-hub.cc/ you can download almost all articles from this site.


www.googlescholar.com    is a good choice for searching an article. If we sign in using our Gmail and search article then our suggested article related to our added publication will also appear. Moreover, our search results will be saved.

www.pubmed.com is also a good choice that can search efficiently against a given author name. It also suggests an article similar to our search in the right side

www.scopus.com is good and give good choice of search. It can download pdf upto 50 articles with author name, date and title in a suggested folder.

www.sciencedirect.com is also good. It suggest similar article that we search and download.

MMGL - Life Sciences by Dr. Muhammad Ali
What is anatomy of a research rticle and how to read an article?

Biochem-720, Evening A, Topics of Research Articles and the designated Week (Thursday 2 PM and sometime Wednesday 2:45 PM)

SrM.Phil. SectionNameDateTopic of research articleAG number e.g. 2019-ag-2662
1Evening AAbdul Basit Ansari 3rd week of OctoberEpiphytic Acampe ochracea orchid relieves paracetamol-induced  hepatotoxicity by inhibiting oxidative stress and upregulating antioxidant  genes in in vivo and virtual screening2021-ag-1853
2Evening AAqsa AmjadIn silico prediction of potential inhibitors for the main protease of SARS-CoV-2 using molecular docking and dynamics simulation based drug-repuposing2017-ag-8423
3Evening AAtiya Imran Mechanistic Details of CRISPR/Cas9 Improve Functional Understanding and Inspire Future Research2021-ag-1854
4Evening AFaria Shahid The initiation of RNA interference (RNAi) in plants 2021-ag-1893
5Evening AFiza Mujahid Reactivation of tumour suppressor in breast cancer by enhancer switching through NamiRNA network2021-ag-1878
6Evening AHareem FatimaDissolvable microneedle patch containing doxorubicin and docetaxel is effective in 4T1 xenografted breast cancer mouse model. 2021-ag-1861
7Evening AMaryamHematological parameters and red blood cell morphological abnormality of Glucose-6-Phosphate dehydrogenase deficiency co-inherited with thalassemia2021-ag- 1921
8Evening AM AQEEL ASHRAFThe impact of the SARS-COV-2 pandemic on the quality of breast cancer care in EUSOMA certified breast center2021-ag-1910
9Evening AMuhammad faizan 4th week of OctoberSilencing alanine transaminase 2 in diabetic liver attenuates hyperglycemia by reducing gluconeogenesis from amino acids2019-ag-2662 
10Evening AShamsa kanwalLignocellulose degrading enzymes production by solid state fermentation through fungal consortium 2021-ag-1842
11Evening AAbeer khizranVitamin D decreases pancreatic iron overload in type 2 diabetes through the NF-κB-DMT1 pathway 
12Evening AAiman Irfan Time-restricted eating with or without low- carbohydrate diet reduces visceral fat and improves metabolic syndrome: A randomized trial 
13Evening AAlia zafarActivation of the insulin receptor by an insulin mimetic peptide 
14Evening AAlisha kanwal Mitochondrially targeted tamoxifen alleviates markers of obesity and type 2 diabetes mellitus in mice 
15Evening AAmina MustafaEnzyme-Powered Nanobots enhance anticancer drug delivery  
16Evening AAmna Nasir Techno-economic analysis of the industrial  production of a low-cost enzyme using E. coli:  the case of recombinant β-glucosidase 
17Evening AAniqa Tariq2nd week of NovemberRegenerative Stem Cell Therapy for Neurodegenerative Diseases: An Overview 
18Evening AAniqa Tariq Genetic in situ engineering of myeloid regulatory cells controls inflammation in autoimmunity 
19Evening AAreej Fatima Breast cancer chemotherapy induces vascular dysfunction and hypertension through a NOX4  – dependent mechanism  
20Evening AAtia Hameed Structural Basis for the Modulation of Human KCNQ4 by Small-Molecule Drugs 
21Evening AAyeshaClimate Change Threatens the microbiological stability of non-refrigerated foods. 
22Evening AAyesha AbbasType 2 diabetes mellitus, its impact on quality of life and how the disease can be managed-a review 
23Evening AAyesha RaufActivation of the human insulin receptor by non-insulin-related peptides 
24Evening AAzhar Shabir Hemophilia gene therapy value assessment: Methodological challenges and recommendations 
25Evening AEimen Rasool3rd week of NovembermTORC1 stimulates cell growth through SAM synthesis and m6A mRNA-dependent control of protein synthesis 
26Evening AEsha ZaheerTucatinib, Trastuzumab, and Capecitabine for HER2-Positive  Metastatic Breast Cancer 
27Evening AFakhra ParveenStem cells: past, present, and future 
28Evening AFatima Nadeemenzymatic production of ethylene glycol  diesters via hydroesterification of used soybean cooking oil 
29Evening AFiza kaleemMetabolic degaradation of lentinan in liver mediated by CYP450 enzymes and epoxide hydrolase 
30Evening AFiza Khan Central role of Prominin-1 in lipid rafts during liver regeneration  
31Evening AGhinaa Siddiqi deletion of skeletal muscle akt1/2 causes osteosarcopenia and reduces lifespan in mice 
32Evening AHafiza Ayesha Tahir Chemotherapy-induced complement signal- ing modulates immunosuppression and metastatic relapse in breast cancer 
33Evening AHafiza Gulnaz Akhtar 4th week of NovemberMyocardial consideration in type-2 diabetes 
34Evening AHafsa KhalidEnzymatic Noncovalent Synthesis for Mitochondrial Genetic Engineering of Cancer Cells 
35Evening AHafsa ShafiqueBY license (http://creativecommons.org/licenses/by/4.0/).Pushing and pulling proteins into the yeast secretory pathway enhances recombinant protein secretion 
36Evening AHira Fatima  
37Evening AIrum Shahzadi Identification of Required Host Factors for SARSCoV-2 Infection in Human CellsNew
38Evening AJavaria Ashfaq  
39Evening AKhadija RasheedEfficient Human Genome Editing Using SaCas9 Ribonucleoprotein Complexes 
40Evening AKinzaDirect Tumor killing and Immunotherapy through  anti-SerpinB9 Therapy  
41Evening AKinza Maqsood 1st week of DecemberLECT2,a ligand for Tie1,plays a crucial role in liver fibrogensis 
42Evening ALaraib Fatima Proinflammatory signaling in islet b cells propagates invasion of pathogenic immune cells in autoimmune diabetesNil
43Evening AMaha NazA tumor cell membrane-coated self-amplified nanosystem as a nanovaccine to boost the therapeutic effect of anti-PD-L1 antibody 
44Evening AMaham Ashfaq  
45Evening AMaira Kanwal Influenza B virus infections in Western Saxony, Germany in three consecutive seasons between 2015 and 2018: Analysis of molecular and clinical features 
46Evening AMaria Asghar Measurements of oxidative stress and total antioxidant capacity in hyperthyroid patients following treatment with carbimazole and antioxidant     
47Evening AMaryam TahirEngineered virus-like particles for efficient in vivo delivery of therapeutic proteins 
48Evening AMehvish majeed The drug-induced phenotypic landscape of colorectal cancer organoids 
49Evening AMinahil Naz2nd week of DecemberNanotechnology-based delivery of CRISPR/Cas9 for cancer treatment  
50Evening AMuhammad Ameer Qarib Naqvi Mesenchymal stem cell therapy for COVID-19: Present or future. 
51Evening AMuhammad imranActivation of the human insulin receptor by non-insulin-related peptides 
52Evening AMuhammad Sultan MahmoodEffect of aWorkplace-Based Multicomponent Intervention on Hypertension Control A Randomized Clinical Trial 
53Evening AMusfirah Gull Translational control through differential ribosome pausing during aa limitation in mammalian cells 
54Evening ANaila MushtaqDirect Tumor Killing and Immunotherapy through Anti-SerpinB9 Therapy 
55Evening ANoor ul ain CRISPR-based genome editing in primary human pancreatic islet cells 
56Evening AQurat ul ain Breast milk mesenchymal stem  cells abate cisplatin‑induced  cardiotoxicity in adult male albino  rats via modulating theAMPK  pathway 
57Evening ARabia Parveen 3rd week of DecemberGene therapy restores adipose tissue and metabolic health in a pre-clinical mouse model of lipodystrophynot registered yet
58Evening ARamshah IqbalAspirin impacts on stem cells: Implications for therapeutic targets 
59Evening ARehana khalidDetection and localization of early- and late-stage cancers using platelet RNA 
60Evening ARida RamzanTet2 Controls the Responses of β cells to Inflammation in Autoimmune Diabetes, Impact factor 17.69Not issued yet 
61Evening ARimsha AnwaarPharmacokinetic analysis identifies a factor VIII immunogenicity threshold after AAV gene therapy in hemophilia A mice 
62Evening ASaba Aslam An evaluation of the psychological impact of early-phase clinical trials in cancer patients 
63Evening ASahar sarwar Diabetes  
64Evening AShanza JamilImpact of serine and serine synthesis genes on H2S release in Saccharomyces  cerevisiae during wine fermentation  
65Evening AShanza khadimTwenty-year trends in heart failure among U.S. adults, 1999–2018: The growing impact of obesity and diabetes 
66Evening ASidra Ahmad4th Week of DecemberStarting the conversation on gene therapy for phenylketonuria: Current perspectives of patients, caregivers, and advocates 
67Evening ASYEDA SUMRAN HASSANHealthcare-associated infection impact with bioaerosol treatment and COVID-19 mitigation measures 
68Evening ATabinda Imtiaz Diabetes  
69Evening AUsama UmarHepatitis B Virus Does Not Interfere With Innate Immune Responses in the Human Liver Suslov, Aleksei et al. Gastroenterology, Volume 154, Issue 6, 1778 – 179 

Biochem-720, Morning A, Topics of Research Articles and the designated Week (Tuesday 11:20 AM and sometime Thursday 8:50 AM)

 M.Phil. SectionNameDateTopic of research articleAG number e.g. 2019-ag-2662
1Morning AArfa Zulfiqar 3rd week of October3D Culture Models with CRISPR Screens Reveal Hyperactive NRF2 as a Prerequisite for Spheroid Formation via Regulation of Proliferation and Ferroptosis2021-ag-1802
2Morning AFaryal AmirInsulin- and Lipopolysaccharide-Mediated Signaling in Adipose Tissue Macrophages Regulates Postprandial Glycemia through Akt-mTOR Activation2017-ag-8439
3Morning AIfra Latif Khan AIFM2 Is Required for High-Intensity Aerobic Exercise in Promoting Glucose Utilization2021-ag-1799
4Morning AMussamra MaryamCRISPR-Cas9 genome editing using targeted lipid nanoparticles for cancer therapy2021-ag-1790
5Morning ARANA ALI HAIDER High‑dimensional hepatopath  data analysis by machine learning  for predicting HBV‑related fbrosis2017-ag-8425
6Morning ARida FatimaEvolution of kinase polypharmacology across HSP90 drug discovery2017-ag-8424
7Morning ARida Fatima4th week of OctoberPhytochemical screening and antidiabetic effects of fruit rind of Momordica dioica roxb. on streptozocin induced type 2 diabetic rats2017-ag-8424 
8Morning ASaman Tahira  Comprehensive and clinically accurate head and neck cancer organs-at-risk delineation on a multi-institutional study2021-ag-1780
9Morning AAhmer AlizaFAMIN Is a Multifunctional Purine Enzyme Enabling the Purine Nucleotide Cycle 
10Morning AAleesha Tariq Tissue-specific impacts of aging and genetics on gene expression patterns in humans 
11Morning AAmara Amin Optimization of growth conditions for the biosynthesis of medium-chain length polyhydroxyalkanoates from Bacillus megaterium DSM 509: experimental analysis, statistical … 
12Morning AArbab amin2nd week of NovemberReducing Akt2 in retinal pigment epithelial cells causes a compensatory increase in Akt1 and attenuates diabetic retinopathy 
13Morning AAreeba Tahseen Neutrophil elastase selectively kills cancer cells and attenuates tumorigenesis 
14Morning AAreej Ahmed Impact of weight loss on brain age: Improved brain health following bariatric surgery.  
15Morning AArshiba khawar SARS-CoV-2 spike protein causes blood coagulation and thrombosis by  competitive binding to heparan sulfate 
16Morning AAtiqa NudratTumor microbiome links cellular programs and immunity in pancreatic cancer 
17Morning AAyesha Mahmood Glutathione Restricts Serine Metabolism to Preserve Regulatory T Cell Function 
18Morning AAyesha Shams3rd week of NovemberMesenchymal stem cell based smad-7 gene therapy for experimental liver cirrhosis  
19Morning AAzam aliEpploring the human lacrimal gland using organoids and single-cell sequencingMphil 1st morning
20Morning AEsha khalidOral delivery of systemic monoclonal antibodies,  peptides and small molecules using gastric  auto-injectors 
21Morning AFaiqa AsgharPhage combination therapies for bacterial wilt disease in tomato 
22Morning AFarah SaghirVitamin D3 administration prevents memory deficit and alteration of biochemical parameters induced by unpredictable chronic mild stress in rats 
23Morning AFariha NazDNA-PKcs promotes fork reversal and chemoresistanceNot alloted yet
24Morning AFatima Anees3rd week of NovemberHigh fructose drives serine synthesis pathway in acute myeloid leukemic cells 
25Morning AHafsa Hussnain A laser-engraved wearable sensor for sensitive  detection of uric acid and tyrosine in sweat33100-8308978-2
26Morning AHafsa Shahzad Acid ceramidase targeting pyruvate kinase affected trypsinogen activation in acute pancreatitis 
27Morning AHifza Saeed A programmable encapsulation system improves  delivery of therapeutic bacteria in mice 
28Morning AHira TahirmiR-15a-5p inhibits metastasis and lipid metabolism by suppressing histone acetylation in lung cancer 
29Morning AIqra Akram Heterotypic cell-in-cell structures between cancer and NK cells are associated with enhanced anticancer drug resistanceM.phil 1st biochemistry 
30Morning AKainat Urooj.4th week of NovemberDeletion of Fructokinase in the Liver or in the Intestine Reveals Differential Effects on Sugar-Induced Metabolic Dysfunction. 
31Morning AKhadija Farhat   
32Morning AKhadija Farhat Mitochondria – endoplasmic reticulum contacts in reactive astrocytes promotes vascular remodeling 
33Morning ALaiqa Ramzan Development of intravenously administered synthetic RNA virus immunotherapy for the treatment of cancerNew Admission 
34Morning ALaraib Ijaz Treatments targeting autophagy ameliorate the age-related macular degeneration phenotype in mice lacking APOE (apolipoprotein E) 
35Morning AM Arslan khanDaily Onset of Light and Darkness Differentially Controls Hematopoietic Stem Cell Differentiation and Maintenance 
36Morning AMahnoor Fatima 1st week of DecemberCurdione ameliorates bleomycin-induced pulmonary fibrosis by repressing TGF-β- induced fibroblast to myofibroblast differentiation 
37Morning AMaleeha SaleemSerine and Lipid Metabolism in Macular Disease and Peripheral Neuropathy 
38Morning AMehreen saleemAcute SARS_COV_2 infection impairs Dendritic cell and T cell Responses. 
39Morning AMUHAMMAD SAFIAL HABIBMultiscale profiling of protease activity in cancer 
40Morning AMuhammad Shahzad MahmoodEffect of Tocilizumab vs  standard care on clinical worsening in patients hospitalized with COVID -19 Pneumonia.A randomized clinicalTrial 
41Morning AMuntaha AhmedKnock-out of 5-lipoxygenase in overexpressing tumor cellsNot yet ( Fresh STUDENT)
42Morning AMuqaddas Saghir2nd week of DecemberAlarming antibiotics resistance  of Helicobacter pylori from children  in Southeast China over 6 years 
43Morning AMusarat Nawazhort Article Fixation and Spread of Somatic Mutations in Adult Human Colonic Epithelium 
44Morning ANimra NazReprogrammed lipid metabolism protects inner nuclear membrane against unsaturated fat 
45Morning ANimra SaeedAn mTORC1-GRASP55 signaling axis controls unconventional secretion to reshape the extracellular proteome upon stress 
46Morning ANoor ul ain Targeted protein degradation reveals RNA Pol II heterogeneity and functional diversity 
47Morning ANuzhat Ejaz HIV specific T cell responses are Highly stable on antiretrival therapy 
48Morning ARohma Nadeem 3rd week of DecemberHypoxia promotes an inflammatory phenotype of fibroblasts in pancreatic cancer. 
49Morning ASamia Farzeen Development of intravenously administered synthetic RNA virus immunotherapy for the treatment of cancer  
50Morning ASana WaheedDifferential mosquito attraction to humans is associated with skin-derived carboxylic acid levels 
51Morning ASara Rehman Fractionating a COVID-19 Ad5-vectored vaccine improves improves virus-specific immunity 
52Morning AShanza Hashim Inflammatory Leptomeningeal Cytokines Mediate COVID-19 Neurologic Symptoms in Cancer Patients 
53Morning AShanza Tariq Electrochemical Fingerprint Biosensor for Natural Indigo Dye Yielding Plants Analysis 
54Morning ASundas Ejaz Blocking Ca2+ Channel beta-3 Subunit Reverses Diabetes 
55Morning ATahreem Tariq Cerebrovascular accidents in sickle cell disease: rates and risk factors  
56Morning ATayyaba Wali Nanotechnology-based delivery of CRISPR/Cas9 for cancer treatment./ Top-Down Control of Sweet and Bitter Taste in the Mammalian Brain 
57Morning AWooda FarooqImpact of time and temperature on the physicochemical, microbiological,  and nutraceutical properties of laver kombucha (Porphyra dentata)  during fermentation  

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