Biochem-505 (Mid-term syllabus) 3(3-0): 

Ch-7 of Lehninger: Carbohydrates: Classification, structures and functions of monosaccharides and oligosaccharides; Hemiacetal and hemiketal structures; Fisher and Howarth projections; Configuration and conformation, boat and chair forms, sugar acids, amino sugars and their derivatives, sialic acids; Biomedical importance of the different carbohydrates; Homopolysaccharides; Starch and glycogen ultrastructure and solution behaviour; Ultrastructure of celluloses, hemicelluloses, gums and pectic substances; Heteropolysaccharides and glycosaminoglycans; Structure, occurrence and functions of hyaluronic acid, heparin, chondriotin sulphates; keratan sulphates and dermatan sulphates. Glycobiology: Structure and functions of glycoconjugates; Current trends and research in the field of glycobiology; 

PLUS………. First 200 MCQs from chapter 2 of the book ” MCQs in Biochemistry”.

Biochem-505 (After mid-term exam):

Chapters 14, 15, and 16 of Lehninger: Blood group polysaccharides and their role in blood grouping; Metabolism of carbohydrates; detailed discussion on glycolysis and its feeder pathways, Krebs cycle, glyoxylate cycle, pentose phosphate cycle and glucuronic acid pathway; Gluconeogenesis and glycogen metabolism; Regulation of carbohydrate metabolism; Inborn errors of carbohydrate.

PLUS………. All MCQs from chapter 2 of the book ” MCQs in Biochemistry”.

Biochem-505: Start preparing your presentations and assignments….. Presentations and Assignment will be taken in first class right after mid-term exam. The presentations will also be started right after mid-term exam.

                                       __________________________________________________________________________________

Assignments and presentations: 

  1. The weightage of the assignment and presentation will be decided later. 
  2. Start preparing your presentations and assignments.
  3. The presentations will also be started right after the mid-term exam.
  4. PPT file should not contain any designing/colours other than figures and diagrams.
  5. Slides should be in 16X9 ratio.
  6. Fonts of all header should be same and of all other text should be same. 
  7. For detailed guidelines about the presentation of research article, visit: https://www.lifesciencesorg.combiochem-720/
  8. Download the template ppt file to make your presentation. The link is here (copy this link and paste in a new tab).
  9. Strictly follow the ppt format and it is better if you write and paste your material in the same ppt file.

K. General Question to be asked during presentation

  1. 1) Pathway or importance of gene/technology/discovery
  2. 2) Rationale
  3. 3) Conclusion of the full article
  4. 4) Conclusion of every figure
  5. 5) New findings presented in the article
  6. 6) Applications of the findings
  7. 7) Future prospective
  8. 8) Applications of the work
  9. 9) Principle of every technique used in the research article

Moreover, provide me a printed summary of your article containing the above headings given under ‘K’.

L. During Presentations, for EVERY FIGURE and graph, we may ask:

1. The Principle of the experiment.
2. The Reason for doing the experiment.
3. The Physiological importance of the figure.
4. The Conclusions of the figure
5. Prepare well objectively and subjectively

NO EXCUSE WILL BE ACCEPTED

______________________________________________________________________________

MCQs will appear from text-book and from chapter 2 of the book ” MCQs in Biochemistry”.

Link to download this book is given below:

https://b-ok.cc/dl/1055171/2292c5

______________________________________________________________________________

Microsoft Teams meeting
Join on your computer, mobile app or room device

Click here to join the meeting

Meeting ID: 316 824 288 013
Passcode: WNyjeA

______________________________________________________________________________

Microsoft teams will be used whenever online classes will be held. You must make your first name as your registration number. 

2017-ag-9382 Haidar Iftikhar

2017-ag-10077 Ahmad Farazesentaino

 

Link to download the book ( MCQs in Biochemistry) is here.

 

BIOCHEM-505            BIOCHEMISTRY OF CARBOHYDRATES              3(3-0)

Theory

Carbohydrates: Classification, structures and functions of monosaccharides and oligosaccharides; Hemiacetal and hemiketal structures; Fisher and Howarth projections; Configuration and conformation, boat and chair forms, sugar acids, amino sugars and their derivatives, sialic acids; Biomedical importance of the different carbohydrates; Homopolysaccharides; Starch and glycogen ultrastructure and solution behaviour; Ultrastructure of celluloses, hemicelluloses, gums and pectic substances; Heteropolysaccharides and glycosaminoglycans; Structure, occurrence and functions of hyaluronic acid, heparin, chondriotin sulphates; keratan sulphates and dermatan sulphates. Glycobiology: Structure and functions of glycoconjugates; Current trends and research in the field of glycobiology; Blood group polysaccharides and their role in blood grouping; Metabolism of carbohydrates; detailed discussion on glycolysis and its feeder pathways, Krebs cycle, glyoxylate cycle, pentose phosphate cycle and glucuronic acid pathway; Gluconeogenesis and glycogen metabolism; Regulation of carbohydrate metabolism; Inborn errors of carbohydrate.

Suggested Readings

  1. Nelson, D.L and M.M. Cox. 2017. Lehninger Principles of Biochemistry. 7th ed. Worth Publishers, New York.
  2. Murray, R., D. Bender,M. Botham, P.J. Kennelly,V. Rodwell and P.A. Weil. 2015. Harper’s Illustrated Biochemistry, 30th edition. The McGraw-Hill companies Inc. USA. ISBN-10: 0071825347
  3. Ferrier, D. R. 2017. Biochemistry: Lippincott’s Illustrated Reviews. 7th Lippincott Williams and Wilkins. U.S.A.
  4. Chatterjea, M. N. and R. Shinde. 2012. Textbook of Medical Biochemistry. 8th ed (Indian edition). Jaypee Brothers, Medical Publishers (P) Ltd, New Delhi, India
  5. Voet, D., Voet, J.G and C.W. Pratt. 2013. Fundamentals of Biochemistry, Life at the Molecular Level. 4th John Wiley & Sons. Inc. New York, NY, USA.
Biochem-505, BS Biochem, 5TH, M-Winter 2023, Dr. Muhammad Ali; 28-08-2023
Sr. Ag No. Student’s Name Group Research article for presentation and 1 page summary
1 2021-ag-8431 Eisha Zahid  G1 Emodin attenuates high lipid-induced liver metastasis through the AKT and ERK pathways in vitro in breast cancer cells and in a mouse xenograft model
2 2021-ag-8441 Linta Shafique
3 2021-ag-8452 Muhammad Haris
4 2021-ag-8458 Muhammad Ramzan
5 2021-ag-8463 Nimra Shoukat
6 2021-ag-8466 Noor-Ul-Ain G2 PRMT6 Regulates RAS/RAF Binding and MEK/ERKMediated Cancer Stemness Activities in Hepatocellular Carcinoma through CRAF Methylation
7 2021-ag-8472 Saliha Nawaz
8 2021-ag-8484 Abdul Qadeer
9 2021-ag-8485 Aleena Khalid
10 2021-ag-8486 Aleeza Tahir
11 2021-ag-8487 Ali Raza G3 Impaired LXRa Phosphorylation Attenuates Progression of Fatty Liver Disease
12 2021-ag-8488 Amna Hamid
13 2021-ag-8490 Anooma
14 2021-ag-8491 Ansa Sehar
15 2021-ag-8492 Areej Fatima Ikram
16 2021-ag-8493 Asnan Saleem G4 Aldolase B-Mediated Fructose Metabolism Drives Metabolic Reprogramming of Colon Cancer Liver Metastasis
17 2021-ag-8494 Ayesha Hassan
18 2021-ag-8495 Ayesha Tahir
19 2021-ag-8496 Esha Batool
20 2021-ag-8497 Esha Mujahid
21 2021-ag-8498 Fatima Haider G5 Treatment of acromegaly by rosiglitazone via upregulating 15-PGDH in both pituitary adenoma and liver
22 2021-ag-8499 Fatima Tahir
23 2021-ag-8500 Ghazia Ashraf
24 2021-ag-8501 Hadia Akram
25 2021-ag-8502 Hafsa Areej
26 2021-ag-8503 Iman Fatima G6 In vivo CRISPR screens identify the E3 ligase Cop1 as a modulator of macrophage infiltration and cancer immunotherapy target
27 2021-ag-8504 Iman Fatima
28 2021-ag-8505 Iqra Javed
29 2021-ag-8507 Kashaf E Noor
30 2021-ag-8509 Khadija Fatima
31 2021-ag-8510 Kiran Arshad G7 Selective Surface PEGylation of UiO-66 Nanoparticles for Enhanced Stability, Cell Uptake, and pH-Responsive Drug Delivery
32 2021-ag-8511 Mahnoor
33 2021-ag-8512 Mahnoor Fatima
34 2021-ag-8513 Manahil Kashif
35 2021-ag-8514 Maryam Naseer
36 2021-ag-8515 Minahil G8 Preventing Allograft Rejection by Targeting Immune Metabolism
37 2021-ag-8517 M.Ahtesham Muhedeen
38 2021-ag-8518 M. Ehtisham Basel
39 2021-ag-8521 Muhammad Shahzad
40 2021-ag-8525 Muqaddas Raza
41 2021-ag-8526 Naila Nawaz G9 Alteration of Tumor Metabolism by CD4+ T Cells Leads to TNF-a-Dependent Intensification of Oxidative Stress and Tumor Cell Death
42 2021-ag-8527 Namal Rauf
43 2021-ag-8528 Nimra Akram
44 2021-ag-8529 Noor Fatima
45 2021-ag-8530 Noor Fatima
46 2021-ag-8531 Noreen Ayesha G10 Controlling cancer-induced inflammation with a nucleic acid scavenger prevents lung metastasis in murine models of breast cancer
47 2021-ag-8532 Rafia Zulfiqar
48 2021-ag-8533 Sadaqat Ali
49 2021-ag-8535 Toima Riaz
50    

Chapter 14 – Glycolysis, Gluconeogenesis, and the Pentose Phosphate Pathway Part 1 (link)

Chapter 14 – Glycolysis, Gluconeogenesis, and the Pentose Phosphate Pathway Part 2 (Link)

Chapter 14 – Glycolysis, Gluconeogenesis, and the Pentose Phosphate Pathway Part 3 (Link)

 

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